Relapse prevention is a central goal in VKH syndrome management. Recurrences can lead to cumulative damage and worsen long-term outcomes.

Gradual reduction of medications under medical supervision minimizes immune rebound. Regular eye examinations help detect early inflammatory changes before symptoms become severe.

Patient education is critical. Recognizing warning signs such as visual blurring or headaches allows for prompt intervention.

Consistency in treatment and follow-up remains the strongest defense against relapse.